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Intraoperative radiotherapy in gynaecological and genito-urinary malignancies: Focus on endometrial, cervical, renal, bladder and prostate cancers

机译:妇科和泌尿生殖系统恶性肿瘤的术中放疗:专注于子宫内膜癌,宫颈癌,肾癌,膀胱癌和前列腺癌

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摘要

Intraoperative radiotherapy (IORT) refers to the delivery of a single radiation dose to a limited volume of tissue during a surgical procedure. A literature review was performed to analyze the role of IORT in gynaecological and genito-urinary cancer including endometrial, cervical, renal, bladder and prostate cancers. Literature search was performed by Pubmed and Scopus, using the words "intraoperative radiotherapy/IORT", "gynaecological cancer", "uterine/endometrial cancer", "cervical/cervix cancer", "renal/kidney cancer", "bladder cancer" and "prostate cancer". Forty-seven articles were selected from the search databases, analyzed and briefly described. Literature data show that IORT has been used to optimize local control rate in genito-urinary tumours mainly in retrospective studies. The results suggest that IORT could be advantageous in the setting of locally advanced and recurrent disease although further prospective trials are needed to confirm this findings.
机译:术中放疗(IORT)是指在外科手术过程中向有限体积的组织中输送单个辐射剂量。进行了文献综述,以分析IORT在包括子宫内膜癌,宫颈癌,肾癌,膀胱癌和前列腺癌在内的妇科和泌尿生殖系统癌症中的作用。 Pubmed和Scopus使用“术中放疗/ IORT”,“妇科癌”,“子宫/子宫内膜癌”,“子宫颈/宫颈癌”,“肾/肾癌”,“膀胱癌”和“ “前列腺癌”。从搜索数据库中选择了47篇文章,对其进行了分析和简要描述。文献数据表明,IORT主要用于回顾性研究中,用于优化生殖泌尿系统肿瘤的局部控制率。结果表明,尽管需要进一步的前瞻性试验来证实这一发现,但IORT在治疗局部晚期和复发性疾病方面可能是有利的。

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